Amphetamine is thought to inhibit monoamine oxidase, whereas the ability of amphetamine and its metabolites to inhibit several P450 isozymes along with other enzymes hasn't been adequately elucidated. In vitro experiments with human microsomes suggest minimal inhibition of CYP2D6 by amphetamine and minor inhibition of CYP1A2, 2D6, and 3A4 by a numb